Having the strongest defensive building in your deck means absolutely nothing if you do not know exactly where to place it on the map.
Novice players tend to panic and place their defensive buildings directly in front of the incoming threat, often right at the bridge.
Mastering the Middle
When the enemy tank crosses the bridge, its AI will calculate that your center turret is closer than your Princess tower, causing it to walk sideways.
As the tank trudges toward the center, it will be simultaneously shot by your defensive building AND both of your Princess towers.
Wait until the tank crosses the bridge before placing it.Protect the blind spot with cheap troops.Vary your placement slightly if they have heavy spells.
Countering the Artillery
Your goal is to use your building as a physical meat shield, absorbing the artillery fire while your troops cross the bridge to destroy it.
Similarly, if the opponent is using 'Spawner' buildings (like Goblin Huts) to create endless lane pressure, placement is key to survival.
Turret TypeBest Tile LocationInferno Tower, CannonThe 'Pocket' - 3 tiles from the river, 3 tiles from the Princess tower; maximizes pull distance and tower crossfireSplash Damage SweepersDirectly in the center, or slightly higher up to intercept fast bridge-spam units before they lock onto the tower
Geometrical Dominance
Every single tile has a specific mathematical value depending on the aggro ranges of the units currently on the board.
Control the geography of the battlefield, dictate the pathing of the enemy, and build an impenetrable wall.
If you want to read more regarding tower rush look into the web-site.